If you have a migraine gut
Threshold Biome™
“Migraines where you get nauseous and throw up.”
Your gut and your brain are wired together. Threshold Biome is a seven-strain probiotic built around that connection, including B. longum and L. plantarum.
How to take it: Take 1 capsule daily with food. One bottle is 30 capsules, one month.
01
The Migraine Gut, in plain English.
People with migraines tend to carry more of the bacteria that shed endotoxin, something your body treats like poison. It keeps pushing on your brain. More pushes, more migraine days.
Every other probiotic is built for your stomach. Threshold Biome is built around the connection between your gut and your brain.
02
How it works
1. The strains settle in. One travels in a shell to survive stomach acid. The rest set up in the gut and stay.
2. Endotoxin has less room to push. They make the gut a poor home for the bacteria that shed it.
3. The wire gets quieter. Fewer pushes along the gut-brain nerve. The mechanism is the research’s; the migraine-day figures in the studies come from trials of multi-strain probiotics, not of this product.
Meet the seven
Seven strains. One capsule a day.
No proprietary blend. Every strain is named down to the species, and each comes with the kind of evidence behind it.
Survives the trip
Bacillus subtilis
A spore-former that travels in a shell instead of dissolving in stomach acid.
The autonomic line
Bifidobacterium breve
In a double-blind human trial, measurably regulated the autonomic nervous system through the gut.
Both ends of the wire
Lactobacillus rhamnosus
Improved gastric motility in one study. In another it calmed anxious behavior, until they cut the vagus nerve. Then the effect vanished.
Tested by name
Bifidobacterium longum
In 2025, tested against the electrical wave behind the zigzag lines. The wave came less often.
Named by the researchers
Lactobacillus plantarum
Reduced the size of that electrical wave, while B. longum reduced how often it came.
The bouncer
Lactobacillus acidophilus
Makes lactic acid, which makes the room inhospitable to the bacteria you do not want. Reduced bloating against placebo in one trial.
The four-month strain
Lactobacillus casei
247 people with vestibular migraine. The probiotic group pulled ahead at four months, not at two.
What happens between today and week 12?
No overnight promise. A plan you can count.
You write down your number
How many migraine days did you have last month? Put it on paper. Most people never do, which is why most people can never tell whether anything is working.
You feel nothing. That is normal.
Good bacteria need weeks to settle in. If you are waiting for a feeling, you are measuring the wrong thing. Take one capsule a day and keep your count.
The study counts. You count too.
This is where the published trial counted, for a multi-strain probiotic, not this product.
You pull out the number from day one
You count again. If the number is lower, you will know. If it is not, you are on day 84 of a 90-day guarantee.
You keep going
In the 247-person vestibular migraine trial, the probiotic group pulled ahead at four months, not at two. This is a slow fix for a slow problem.
The Threshold Protocol
Build it on the foundation.
Biome works on your gut. Threshold Daily gives your brain more room under your line every day.
See Threshold Daily ⇒
Try it for 90 days. If it isn’t for you, you get every dollar back.
Same promise on every product. Email us and we’ll refund you. No forms. No hoops. No questions asked.
Questions
How do I take it?
Take 1 capsule daily with food, at roughly the same point in your day. One bottle is 30 capsules, so one bottle is one month. Plan on at least 12 weeks, which is what the 3-bottle and 6-bottle packs cover.
Who should check with a doctor first?
Not intended for children. If you are pregnant, breastfeeding, immunocompromised or taking prescription medication, speak to your healthcare provider before starting any new supplement.
How does the 90-day guarantee work?
If you decide within 90 days that it isn’t for you, email sarah@thresholddaily.com and we’ll refund you. No forms. No hoops.
Can I take this with my medication?
Check with your doctor or pharmacist before starting anything new. For a question about a specific medication, email us and a person will answer.
Does it ship free?
Free US shipping on 3 and 6 bottles. One bottle ships for $4.95.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease. Individual results vary. Consult your healthcare provider before starting any new supplement, especially if you are pregnant, breastfeeding, or taking prescription medication.
Juliets Herbal Secrets · 30 N Gould St Ste R, Sheridan, WY 82801 · sarah@thresholddaily.com